Intervenční a akutní kardiologie v desátém ročníku

prof. MUDr. Jan Vojáček, DrSc., FESC, FACC

Interv Akut Kardiol. 2011;10(2):47  

Akutní aortální disekce - novinky nebo zkušenosti ?

Jaroslav Benedík

Interv Akut Kardiol. 2011;10(2):52-53  

A new technique of catheter mitral paravalvular leak closure

Jaroslav Januška, Marian Branny, Martin Fiala, Miroslav Dorda, Petr Malík, Josef Nečas, Martin Mates, Petr Neužil

Interv Akut Kardiol. 2011;10(2):54-56  

Aim: The aim of this paper is to introduce new technic of mitral paravalvular leak (MiPVL) closure using steerable electrophysiologic catheter. Method and Results: We made six attempts to close MiPVL. Procedure was performed under general anesthesia with simultaneous monitoring of 3D transesophageal echocardiography (RT3DTEE) except one. In five cases, we didnot cross MiPVL in a standard manner, only in one case we have been succefull applying the conventional technique. In all cases we were able to pass the channel MPVL from the left atrium into the left ventricle. In one case, we made the closure twice, because the Amplatzer VSD occluder...

Acetylosalicylic acid efficacy assessment in patients with stable coronary artery disease

Hana Ševčíková, Jan Vojáček, Josef Bis, Robert Ševčík

Interv Akut Kardiol. 2011;10(2):58-60  

Inadequate platelet suppression by acetylosalicylic acid is a relatively well known phenomenon in cardiology. How to define it properly ? Persistent high residual platelet reactivity or treatment failure seems to be the best term. There are several reasons for an inadequate platelet suppression and several techniques may be used to assess platelet function and the effectiveness of antiplatelet therapy. The role of inflammation and genetic polymorphisms in high residual platelet activity and atherothrombosis was studied with inconsistent results. There are still no clinical data to support change in antiplatelet therapy in the correlation with...

Strategy of atrial fibrillation antiarrhythmic treatment in patients with valvular heart disease

Petr Heinc, Tomáš Skála, Miloš Táborský, Jan Václavík

Interv Akut Kardiol. 2011;10(2):62-66  

Atrial fibrillation is the most worldwide-sustained arrhythmia and in about 20–30 % of patients in atrial fibrillation valvular heart disease is present. Minimalization of symptoms and prevention of complications (heart failure) is fundamental treatment of both issues. Strategy of rhythm control and rate control wth respect of valvular heart disease presentation is mentioned and the position of radiofrequency ablation is indicated.

Glycaemic control in patients with acute myocardial infarction

Jan Šoupal, Martin Prázný

Interv Akut Kardiol. 2011;10(2):67-71  

Numerous observational studies indicate that patients with diabetes are at a higher risk of developing cardiovascular diseases including myocardial infarction. In the long term, tight diabetes control leads to a reduced risk of developing cardiovascular complications and diabetic patients clearly benefit from it. However, our knowledge of the benefits of tight glycaemic control in patients with acute myocardial infarction remains limited even though these patients are frequently found to have stress hyperglycaemia. Some of the recent studies have shown that hyperglycaemia in the critically ill is associated with a higher morbidity and mortality...

Cholesterol embolization syndrome

Marián Fedorco, Martin Tichý, Martin Hutyra, Miloš Táborský

Interv Akut Kardiol. 2011;10(2):72-76  

Cholesterol embolization syndrome is an atherosclerosis complication, characterized by peripheral embolization of atherosclerotic mass, especially by cholesterol crystals. Cholesterol crystals lead to end-organ damage, due to inflammatory reaction and ischemia caused by arterial occlusion. The origin of emboli is from thoracic, abdominal aorta and proximal large-caliber arteries. Elderly with atherosclerosis risk factors are usually affected group. The cholesterol embolization syndrome can usually be seen after catheterization, cardiac and vascular surgery. Authors demonstrate in the own case report the difficulties of the syndrome diagnosis...

The magnetic resonance heart examination as a differential diagnostic method to detection

Martin Porzer, Pavla Hanzlíková, Miroslav Homza

Interv Akut Kardiol. 2011;10(2):78-80  

of etiology of acute heart failure with development of multiple organ dysfunction syndrome This case report refers to a case, in which the heart examination by magnetic resonance was selected as a differential diagnostic method to differentiate between inflammatory and non-inflammatory lesion of myocardium with advancement of acute global cardiac failure with subsequent development of multiple organ dysfunction syndrome. The examination, failing to prove myocarditis, allowed for acute surgery of the patient – aortic valve replacement, which led to a prompt stabilization of the acute state of the patient and gradual normalization of...

Dabigatran etexilate - a breakthrough in antithrombotic therapy in cardiology?

Petr Janský

Interv Akut Kardiol. 2011;10(2):82-86  

Dabigatran etexilate belongs to a new group of anticoagulants – oral direct thrombin inhibitors. It has favourable pharmacological properties which enable uniform dosage without a need for monitoring of the anticoagulant effect. The efficacy and safety of dabigatran have been established in a number of clinical trials focused on the prevention and treatment of venous thromboembolism. RE-LY, a recently published trial in patients with atrial fibrillation, demonstrated a reduced risk of stroke and systemic embolism with dabigatran treatment compared to warfarin as well as a low risk of bleeding and a significant reduction in haemorrhagic...