Jaká je skutečná chybovost hladiny významnosti p < 0,05 a proč nepoužívat označení statisticky významný/nevýznamný rozdíl

Jan F. Vojáček

Interv Akut Kardiol. 2022;21(2):64-70 | DOI: 10.36290/kar.2022.017  

Left bundle branch area pacing is a physiological alternative to the right ventricular/biventricular pacing - the results of implantation center registry

Karol Čurila, Petr Štros, Jan Mizner, Ondřej Süssenbek, Jakub Karch, Markéta Sušánková, Lucie Znojilová, Dalibor Heřman, Pavel Osmančík

Interv Akut Kardiol. 2022;21(2):72-78 | DOI: 10.36290/kar.2022.008  

Summary: Left bundle branch area pacing (LBBAP) is a new method of pacing in patients who have bradycardia or are indicated to receive cardiac resynchronization therapy (CRT). Data on intraoperative and postoperative outcomes of this method are lacking.  Methods: All patients with bradycardia or an indication for CRT, who underwent LBBAP during a surgical procedure at the Heart Centre of the Kralovske Vinohrady University Hospital and the Third Faculty of Medicine of Charles University in the period from 11/2018 to 05/2021, were included in the registry. Most patients were included in the registry in a prospective manner, and selected parameters were...

Effect of precipitating factors and signs of acute heart failure on length of hospital stay

Jiří Dokoupil, Juraj Hrečko, Eva Čermáková, Radek Pudil

Interv Akut Kardiol. 2022;21(2):79-83 | DOI: 10.36290/kar.2022.013  

Aim: We aimed to assess the impact of precipitating factors and signs of acute heart failure on the length of hospital stay according to the ejection fraction (EF) subgroups. Methods: We conducted a retrospective study among acute heart failure patients hospitalized at the Department of Cardioangiology in 2017. The most frequent precipitants and signs were included in the multivariate analysis to assess their association with the length of hospital stay. Results: We included 376 patients with a median length of hospital stay 11 days. There were 198, 58, and 120 patients with reduced, mildly reduced, and preserved EF, respectively. In reduced EF,...

The use and safety of sutureless aortic valve replacement in combined valve procedures

Marián Kohut, Jiří Vaněk, Mahmoud Al-Obeidallah, Patrik Roučka, Vlasta Šťastná, Marta Zárybnická, Tomáš Hájek

Interv Akut Kardiol. 2022;21(2):84-87 | DOI: 10.36290/kar.2022.012  

Sutureless aortic valve replacement is associated with shorter aortic crossclamp times and lower pressures in small aortic roots. Available data are limited on the use of this sutureless method in combined cardiac surgery valve replacement. Combined cardiac surgery valve procedures using a sutureless valve in the aortic position were performed in 11 patients between 2015 and 2020 at the Department of Cardiac Surgery of the University Hospital in Pilsen. The logistic EUROSCORE was 17 ± 7,68, and the aortic cross clamp time 74 ± 11.8 minutes. A benefical postoperative hemodynamic effect was observed in all cases. Only one person with a very...

Decision aid rules for patients with suspected acute coronary syndrome

Juraj Hrečko, Jiří Dokoupil, Radek Pudil

Interv Akut Kardiol. 2022;21(2):88-95 | DOI: 10.36290/kar.2022.010  

The number of examinations for acute chest pain in developed countries is rising. The differential diagnosis for chest pain is wide and, even with the use of modern technologies, it is often impossible to determine the exact cause. The choice of optimal diagnostic modalities for a logical and meaningful strategy remains challenging. Decision aid rules have been created for a quick and effective management of patient with chest pain in acute care. They are mentioned in European and American guidelines. This article aims to present an overview of available models for the decision making in the emergency department and explain their benefits, limitations...

Use of intravenous beta blockers in current acute cardiology

Tomáš Janota

Interv Akut Kardiol. 2022;21(2):96-100 | DOI: 10.36290/kar.2022.014  

Intravenous beta blockers have proven to be a reliable class of medications in treating tachyarrhythmias of various underlying causes and in managing severe hypertension. There is an ever-growing number of indications for the use of beta blockers, since the vast majority of medical emergencies result in extreme catecholamine secretion, leading to associated side-effects. These side-effects can be prevented by using beta blockers. Recent findings support the idea that beta blockers can be beneficial in sepsis, shock, acute heart failure, trauma, thermal trauma, and other medical emergencies associated with tachycardia or tachyarrhythmia. Beta blockers...

Recent negative FFR trials: possible causes and consequences

Tomáš Kovárník, Štěpán Jeřábek, Karel Kopřiva, Jan Pudil

Interv Akut Kardiol. 2022;21(2):101-107 | DOI: 10.36290/kar.2022.015  

The authors present the results of recently published trials evaluating fractional flow reserve in the treatment strategy of patients with both stable forms of coronary artery disease and acute coronary syndrome. The aim is to comment on the trial results and their possible impact on routine clinical practice.

High­‑risk PCI using Shockwave intravascular lithotripsy and iVAC2L support in a Covid-19 positive patient: a case report

Milan Dragula, Lukáš Urban, Ivana Ságová, Jurina Sadloňová, Miloš Kňazeje

Interv Akut Kardiol. 2022;21(2):108-111 | DOI: 10.36290/kar.2022.009  

At the time of the ongoing coronavirus pandemic, we are encountering patients who are Covid-19 positive and have severe coronary artery disease. Patients requiring cardiac surgery are particularly challenging. A multidisciplinary discussion aimed at assessing surgery tolerability and considering the most appropriate approach is important given the higher risk of surgical mortality. We report a case of a high-risk Covid-19 positive symptomatic female patient with an acute coronary syndrome and a critical calcified stenosis of the main stem of the left coronary artery. This patient was not suitable for cardiac surgery and she underwent a percutaneous...

Profesor Jan Vojáček slaví 75 let

Doc. MUDr. Josef Šťásek, Ph.D.

Interv Akut Kardiol. 2022;21(2):112-113  

Doc. MUDr. Karel Hlaváček, CSc., slaví osmdesát

MUDr. David Horák, prof. MUDr. Petr Ošťádal, Ph.D.

Interv Akut Kardiol. 2022;21(2):114