Interv Akut Kardiol. 2009;8(3):121-123

Is angioplasty for atherosclerotic renal artery stenosis beneficial in managing hypertension ?

Ivo Varvařovský¹, Aleš Herman¹, Jan Matějka², Vladimír Rozsíval¹

¹ Kardio-Troll, pracoviště invazivní kardiologie, Krajská nemocnice, Pardubice

² Kardiologické oddělení Krajské nemocnice Pardubice

Introduction: Renal artery stenosis may result in an increase in blood pressure and the development of renal insufficiency; however, the

dilatation of stenosis using renal angioplasty has an indeterminate effect on the course of these conditions.

Objective: To assess the effect of percutaneous transluminal renal artery angioplasty (PTRA) on the course of hypertensive disease.

Methods: A retrospective study of the course of hypertensive disease in patients managed with PTRA at a single centre.

Results: In 26 patients, there was a significant decrease in the systolic (from 159 to 143 mm Hg, p = 0.02), diastolic (from 84 to 78 mm Hg,

p = 0.04) as well as mean blood pressures (from 108 to 100 mm Hg, p = 0.01), with a mean follow-up period of 8.6 months. The consumption

of antihypertensive drugs decreased significantly (from 3.56 to 2.38, p = 0.001). The group of patients with a favourable response to

PTRA (a decrease in the mean blood pressure by more than 10 mm Hg) was characterized by a significantly poorer initial management

of hypertension associated with an insignificantly higher number of antihypertensive drugs.

Conclusion: Angioplasty for atherosclerotic renal artery stenosis is beneficial in the management of hypertension, particularly in those

patients with poorly controlled hypertension and with a high consumption of antihypertensive drugs.

Keywords: renal artery angioplasty, hypertension.

Published: July 15, 2009  Show citation