Interv Akut Kardiol. 2024;23(2-3):64-68 | DOI: 10.36290/kar.2024.020

Pulmonary embolism: prophylaxis, diagnosis, acute therapy

Martin Radvan, Martin Kameník
Interní kardiologická klinika, Fakultní nemocnice Brno a Lékařská fakulta Masarykovy univerzity, Brno

Pulmonary embolism is the third most common cardiovascular reason for death after myocardial infarction and stroke. The principles of thromboembolic disease prophylaxis are an integral part of care in both surgical and internal medicine. The severity of pulmonary embolism ranges across the spectrum, from completely asymptomatic forms to obstructive shock, where the first and only symptom is sudden death. The mainstay of treatment for low- and intermediate-risk patients is anticoagulation therapy. For high-risk patients, effective thrombolytic therapy is available, but it has a number of contraindications and, even if these are respected, carries a risk of bleeding, including fatal. Until recently, the only alternative, cardiosurgical embolectomy, is now being replaced by widening spectrum of cathetrization techniques.

Keywords: plicní embolie, profylaxe, katetrizační léčba, trombolýza.

Received: October 29, 2024; Accepted: October 29, 2024; Published: December 12, 2024  Show citation

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Radvan M, Kameník M. Pulmonary embolism: prophylaxis, diagnosis, acute therapy. Interv Akut Kardiol. 2024;23(2-3):64-68. doi: 10.36290/kar.2024.020.
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References

  1. Pepke-Zaba J, Delcroix M, Lang I, Mayer E, Jansa P, Ambroz D, et al. Chronic thromboembolic pulmonary hypertension (CTEPH): results from an international prospective registry. Circulation. 2011 Nov 1;124(18):1973-81. Go to original source... Go to PubMed...
  2. Wirchow R. Virchow, R. 'Thrombose und Embolie. Gefässentzündung und septische Infektion'. Gesammelte Abhandlungen zur wissenschaftlichen Medicin (in German). Frankfurt am Main: Von Meidinger & Sohn; 1856. pp. 219-732.Matzdorff AC, Bell WR (1998). Thrombosis and embolie (1846-1856). Canton, Massachusetts: Science History Publications. ISBN 0-88135-113-X.
  3. Stein PD, Matta F, Keyes DC, Willyerd GL. Impact of vena cava filters on in-hospital case fatality rate from pulmonary embolism. Am J Med. 2012 May;125(5):478-84. Go to original source... Go to PubMed...
  4. Straka M, Hustý J, Rohan T, Radvan M, Sůva M. Kavální filtry - zkušenosti jednoho pracoviště.
  5. Konstantinides SV, Meyer G, Becattini C, Bueno H, Geersing GJ, Harjola VP, et al. 2019 ESC Guidelines for the diagnosis and management of acute pulmonary embolism developed in collaboration with the European Respiratory Society (ERS). Eur Heart J. 2020 Jan 21;41(4):543-603. Go to original source... Go to PubMed...
  6. Voběrková H, Kočka V, Kroupa J. Akutní plicní embolie -současné možnosti intervenční léčby. Intervenční a akutní kardiologie. 2023 Nov 28;22(4):189-93. Go to original source...




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