Interv Akut Kardiol. 2021;20(4):228-232 | DOI: 10.36290/kar.2021.032

Pulmonary hypertension in childhood

Karel Koubský1, Ondřej Materna1, Tereza Doušová2, Václav Chaloupecký1
1 Dětské kardiocentrum 2. lékařské fakulty Univerzity Karlovy v Praze a Fakultní nemocnice v Motole, Praha
2 Pediatrická klinika 2. lékařské fakulty Univerzity Karlovy a Fakultní nemocnice v Motole, Praha

Pediatric pulmonary hypertension (PH) is a serious disease which shares many features with pulmonary hypertension in adults, but also has many differences, especially in terms of the etiology, clinical symptoms, and prognosis. This article is based on the latest guidelines for the diagnosis and treatment of pediatric PH and summarizes the most frequent diseases associated with PH in children.

Keywords: pulmonary hypertension, congenital heart defect, vasodilators, catheterization, child.

Received: October 21, 2021; Revised: October 21, 2021; Accepted: October 21, 2021; Prepublished online: October 21, 2021; Published: November 23, 2021  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Koubský K, Materna O, Doušová T, Chaloupecký V. Pulmonary hypertension in childhood. Interv Akut Kardiol. 2021;20(4):228-232. doi: 10.36290/kar.2021.032.
Download citation

References

  1. Rosenzweig EB, Abman SH, Adatia I, et al. Paediatric pulmonary arterial hypertension: updates on definition, classification, diagnostics and management. The European respiratory journal. 2019; 53. Go to original source... Go to PubMed...
  2. Hansmann G, Koestenberger M, Alastalo TP, et al. 2019 updated consensus statement on the diagnosis and treatment of pediatric pulmonary hypertension: The European Pediatric Pulmonary Vascular Disease Network (EPPVDN), endorsed by AEPC, ESPR and ISHLT. Journal of Heart and Lung Transplantation. 2019; 38: 879-901. Go to original source... Go to PubMed...
  3. Chaloupecký, V. Plicní hypertenze v dětském věku. In: Jansa P, Aschermann M. Chronická plicní hypertenze. Praha, Maxdorf 2017: 311-316.
  4. Apitz C, Hansmann G, Schranz D. Hemodynamic assessment and acute pulmonary vasoreactivity testing in the evaluation of children with pulmonary vascular disease. Expert consensus statement on the diagnosis and treatment of paediatric pulmonary hypertension. The European Paediatric Pulmonary Vascular Disease Network, endorsed by ISHLT and DGPK. Heart. 2016; 102: ii23-ii29. Go to original source... Go to PubMed...
  5. Chaix MA, Gatzoulis MA, Diller GP, Khairy P, Oechslin EN. Eisenmenger Syndrome: A Multisystem Disorder-Do Not Destabilize the Balanced but Fragile Physiology. The Canadian journal of cardiology. 2019; 35: 1664-1674. Go to original source... Go to PubMed...
  6. Mandell E, Kinsella JP, Abman SH. Persistent pulmonary hypertension of the newborn. Pediatric Pulmonology. 2021; 56: 661-669. Go to original source... Go to PubMed...
  7. Thébaud B, Goss KN, Laughon M, et al. Bronchopulmonary dysplasia. Nature Reviews Disease Primers. 2019; 5: 1-23. Go to original source... Go to PubMed...
  8. Mourani PM, Abman SH. Pulmonary Hypertension and Vascular Abnormalities in Bronchopulmonary Dysplasia. Clinics in Perinatology. 2015; 42: 839-855. Go to original source... Go to PubMed...
  9. Puligandla PS, Skarsgard ED, Offringa M, et al. Diagnosis and management of congenital diaphragmatic hernia: a clinical practice guideline. CMAJ. 2018; 190: E103-E112. Go to original source... Go to PubMed...
  10. Kraemer US, Leeuwen L, Krasemann TB, Wijnen RMH, Tibboel D, IJsselstijn H. Characteristics of infants with congenital diaphragmatic hernia who need follow-up of pulmonary hypertension. Pediatric Critical Care Medicine. 2018; 19: E219-E226. Go to original source... Go to PubMed...
  11. Kam CW, Ruiz FE. Opportunities and challenges of pharmacotherapy for pulmonary arterial hypertension in children. Pediatric pulmonology. 2021; 56: 593-613. Go to original source... Go to PubMed...
  12. Hansmann G, Meinel K, Bukova M, Chouvarine P, Wåhlander H, Koestenberger M. Selexipag for the treatment of children with pulmonary arterial hypertension: First multicenter experience in drug safety and efficacy. Journal of Heart and Lung Transplantation. 2020; 39: 695-706. Go to original source... Go to PubMed...
  13. Hayes D, Jr, Cherikh WS, et al. The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: Twenty-second pediatric lung and heart-lung transplantation report - 2019; Focus theme: Donor and recipient size match. Journal of Heart and Lung Transplantation. 2019; 38: 1015. Go to original source... Go to PubMed...




Interventional Cardiology

Madam, Sir,
please be aware that the website on which you intend to enter, not the general public because it contains technical information about medicines, including advertisements relating to medicinal products. This information and communication professionals are solely under §2 of the Act n.40/1995 Coll. Is active persons authorized to prescribe or supply (hereinafter expert).
Take note that if you are not an expert, you run the risk of danger to their health or the health of other persons, if you the obtained information improperly understood or interpreted, and especially advertising which may be part of this site, or whether you used it for self-diagnosis or medical treatment, whether in relation to each other in person or in relation to others.

I declare:

  1. that I have met the above instruction
  2. I'm an expert within the meaning of the Act n.40/1995 Coll. the regulation of advertising, as amended, and I am aware of the risks that would be a person other than the expert input to these sites exhibited


No

Yes

If your statement is not true, please be aware
that brings the risk of danger to their health or the health of others.