Interv Akut Kardiol. 2019;18(4):239-242

ISAR REACT 5: acute concern or storm in a teacup?

Ivo Varvařovský
Kardiologické centrum Agel, Pardubice

Aggressive antiplatelet therapy is the cornerstone for acute coronary syndrome treatment. Acute phase therapy is based on the
dual antiplatelet treatment (DAPT) with highly effective inhibitors of the platelet receptor P2Y12. The ISAR-REACT 5 trial directly
compare ticagrelor and prasugrel in two different antiplatelet strategies. The result of both efficacy and safety are contrary to
current knowledge and needs to be carefully validated.

Keywords: acute coronary syndrome, dual antiplatelet therapy, prasugrel, ticagrelor

Published: December 1, 2019  Show citation

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Varvařovský I. ISAR REACT 5: acute concern or storm in a teacup? Interv Akut Kardiol. 2019;18(4):239-242.
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