Interv Akut Kardiol. 2016;15(3):141-144 | DOI: 10.36290/kar.2016.028

Arterial hypertension and optimal therapy options

Dagmar Vondráková
Kardiovaskulární centrum, Nemocnice Na Homolce, Praha

Arterial hypertension is a significant worldwide health problem with the high global prevalence. Although individuals with hypertension

have an increased cardiovascular risk, the optimal blood pressure control in these patients remains inadequate. According

to the available evidence, the fixed combination of antihypertensive drugs may improve adherence to the therapy and increases

achievement of blood pressure targets.

Keywords: arterial hypertension, combination therapy, fixed combination

Published: October 1, 2016  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Vondráková D. Arterial hypertension and optimal therapy options. Interv Akut Kardiol. 2016;15(3):141-144. doi: 10.36290/kar.2016.028.
Share...
Download citation
  • BibTeX (.bib)
  • Bookends (.ris)
  • EasyBib (.ris)
  • EndNote (.enw)
  • EndNote 8 (.xml)
  • ISI WoS (.isi)
  • Medlars (.medlars)
  • Mendeley (.ris)
  • MODS (.xml)
  • Papers (.ris)
  • RefWorks (.txt)
  • RefManager (.ris)
  • RIS (.ris)
  • MS Word (.xml)
  • Zotero (.ris)
    • Open full article

    References

    1. Kearney PM, Whelton M, Reynolds K, et al. Global burden of hypertension: analysis of world wide data. Lancet. 2005; 365(9455): 217-223. Go to original source... Go to PubMed...
    2. Jaddou HY, Batieha AM, Khader YS, et al. Hypertension Prevalence, awareness, Treatment and Control, and Associated Factors: Results from a National Survey, Jordan. International Journal of Hypertension, 2011: 1-9. Go to original source... Go to PubMed...
    3. Cífková R, Bruthans J, Adámková V, et al. Prevalence základních kardiovaskulárních rizikových faktorů v české populaci v letech 2006-2009. Studie Czech post-MONICA. CorVasa 2011; 53: 220-229. Go to original source...
    4. Israil ZH, Hernandez R, Valasco M. The future of antihypertensive treatment. American Journal of Therapeutics, 2007; 14(2): 121-134. Go to original source... Go to PubMed...
    5. Lewington S, Clarke R, Qizilbash N, et al. Prospective Studies Collaboration. Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies. Lancet. 2002 Dec 14; 360(9349): 1903-1913. Go to original source... Go to PubMed...
    6. Gerstein C, et al. Effects of Intensive Glucose Lowering in Type 2 Diabetes. The Action to Control Cardiovascular Risk in Diabetes Study Group. N Engl J Med 2008; 358: 2545-2559. Go to original source...
    7. Mancia G, Fagard R, Narkiewicz K, et al. ESH/ESC guide ines for the management of arterial hypertension: the Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). Eur Hear J. 2013; 34: 2159-2219. Go to original source... Go to PubMed...
    8. Chow CK, Teo KK, Rangarajan S, et al. PURE (Prospective Urban Rural Epidemiology) Study investigators. Prevalence, awareness, treatment, and control of hypertension in rural and urban communities in high-, middle-, and low-income countries. JAMA. 2013; 310(9): 959-968. Go to original source... Go to PubMed...
    9. Frank J, Managing hypertension using combination therapy, Am Fam Physician. 2008; 77(9): 1279-1286. Go to PubMed...
    10. Thoenes M, Neuberger HR, Volpe M, et al. Antihypertensive drug therapy and blood pressure control in men and women: an international perspective. J Hum Hypertens. 2010; 24(5): 336-344. Go to original source... Go to PubMed...
    11. Neutel JM, Smith DH. Hypertension management: rationale for triple therapy based on mechanisms of action. Cardiovasc Ther. 2013; 31(5): 251-258. Go to original source... Go to PubMed...
    12. Gradman AH, Parise H, Lefebvre P, at al. Initial combination therapy reduces the risk of cardiovascular events in hypertensive patients, a matcehd cohort study. Hypertension. 2013; 61: 309-318. Go to original source... Go to PubMed...
    13. Wald DS, Law M, Morris JK. Combination therapy versus monotherapy in reducing blood pressure: meta-analysis on 11,000 participants from 42 trials. Am J Med. 2009; 122(3): 290-300. Go to original source... Go to PubMed...
    14. Arwood MJ, Cavallari LH, Duarte JD. Pharmacogenomics of hypertension and heartdisease. Curr Hypertens Rep. 2015; 17(9): 586. Go to original source... Go to PubMed...
    15. Dahlöf B, Sever PS, Poulter NR, et al. ASCOT Investigators. Prevention of cardiovascular events with an antihypertensive regimen of amlodipine adding perindopril as required versus atenolol addingbendr of lumethiazide as required, in the Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm (ASCOT-BPLA): a multicentre randomised controlled trial. Lancet. 2005; 366(9489): 895-906. Go to original source... Go to PubMed...
    16. PROGRESS Collaborative Group. Randomised trial of a perindopril-based blood-pressure-lowering regimen among 6, 105 individuals with previous stroke or transient ischaemic attack. Lancet.2001; 358(9287): 1033-1041. Go to original source... Go to PubMed...
    17. Patel A, MacMahon S, Chalmers J, et al. Effects of a fixed combination of perindopril and indapamid on macrovascular and microvascular outcomes in patients with type 2 diabetes mellitus (the ADVANCE trial): a randomised control trial. Lancet. 2007; 370(9590): 829-840. Go to original source... Go to PubMed...
    18. Beckett NS, Peters R, Fletcher AE, at al. Treatment of hypertension in patients 80 years of age or older. NEngl J Med 2008; 358:1887-1898. Go to original source... Go to PubMed...
    19. Toth K, at al. Antihypertensive Efficacy of Triple Combination Perindopril/Indapamide Plus Amlodipie in High-Risk Hypertensives: Results of the PIANIST Study (Perindopril-Indapamide plus AmlodipiNe in high rISk hyperTensive patients). Am J Cardiovasc Drugs. 2014; 14: 137-145. Go to original source... Go to PubMed...

    Return to the content


    Interventional Cardiology

    Madam, Sir,
    please be aware that the website on which you intend to enter, not the general public because it contains technical information about medicines, including advertisements relating to medicinal products. This information and communication professionals are solely under §2 of the Act n.40/1995 Coll. Is active persons authorized to prescribe or supply (hereinafter expert).
    Take note that if you are not an expert, you run the risk of danger to their health or the health of other persons, if you the obtained information improperly understood or interpreted, and especially advertising which may be part of this site, or whether you used it for self-diagnosis or medical treatment, whether in relation to each other in person or in relation to others.

    I declare:

    1. that I have met the above instruction
    2. I'm an expert within the meaning of the Act n.40/1995 Coll. the regulation of advertising, as amended, and I am aware of the risks that would be a person other than the expert input to these sites exhibited

    No
    Yes

    If your statement is not true, please be aware
    that brings the risk of danger to their health or the health of others.