Interv Akut Kardiol. 2015;14(2):74-76

Renal denervation: What is its current position?

Ján Rosa, Jiří Widimský jr.
Centrum pro výzkum, diagnostiku a léčbu arteriální hypertenze VFN a 1. LF UK, Praha

Recent studies on catheter-based renal denervation have failed to demonstrate the efficacy of this method in order for it to be implemented

into routine practice. Further research should be undertaken in specialized centres with the aim to identify patients who might

benefit from this treatment modality.

Keywords: arterial hypertension, catheter-based renal denervation

Published: June 1, 2015  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Rosa J, Widimský J. Renal denervation: What is its current position? Interv Akut Kardiol. 2015;14(2):74-76.
Share...
Download citation
  • BibTeX (.bib)
  • Bookends (.ris)
  • EasyBib (.ris)
  • EndNote (.enw)
  • EndNote 8 (.xml)
  • ISI WoS (.isi)
  • Medlars (.medlars)
  • Mendeley (.ris)
  • MODS (.xml)
  • Papers (.ris)
  • RefWorks (.txt)
  • RefManager (.ris)
  • RIS (.ris)
  • MS Word (.xml)
  • Zotero (.ris)
    • Open full article

    References

    1. Cífková R, et al. Longitudinal trends in major cardiovascular risk factors in the Czech population between 1985 and 2007/8. Czech MONICA and Czech post-MONICA. Atherosclerosis, 2010; 211(2): 676-681. Go to original source... Go to PubMed...
    2. Mancia G, et al. 2013 ESH/ESC guidelines for the management of arterial hypertension: the Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). Eur Heart J, 2013; 34(28): 2159-2219. Go to original source... Go to PubMed...
    3. Štrauch B, et al. Precise assessment of noncompliance with the antihypertensive therapy in patients with resistant hypertension using toxicological serum analysis, in Journal of hypertension 2013: 2455-2461. Go to original source... Go to PubMed...
    4. Carey RM. Resistant hypertension. Hypertension, 2013; 61(4): 746-750. Go to original source... Go to PubMed...
    5. Morrissey DM, Brookes VS, Cooke WT. Sympathectomy in the treatment of hypertension; review of 122 cases. Lancet, 1953; 1(6757): 403-408. Go to original source...
    6. Schlaich MP, et al. Renal sympathetic-nerve ablation for uncontrolled hypertension. N Engl J Med, 2009; 361(9): 932-934. Go to original source...
    7. Esler MD, et al. Renal sympathetic denervation for treatment of drug-resistant hypertension: one-year results from the Symplicity HTN-2 randomized, controlled trial. Circulation, 2012; 126(25): 2976-2982. Go to original source...
    8. Esler MD, et al. Renal sympathetic denervation in patients with treatment-resistant hypertension (The Symplicity HTN-2 Trial): a randomised controlled trial. Lancet, 2010; 376(9756): 1903-1909. Go to original source...
    9. Symplicity HTN-1 Investigators, Catheter-based renal sympathetic denervation for resistant hypertension: durability of blood pressure reduction out to 24 months. Hypertension, 2011; 57(5): 911-917. Go to PubMed...
    10. Widimský P, et al. Expert consensus statement of the Czech Society of Cardiology and the Czech Society of Hypertension on catheter-based sympathetic renal denervation procedures (RDN) in the Czech Republic. Cor et Vasa, 2012; 54(2): e108-e112. Go to original source...
    11. Krum H, et al. Catheter-based renal sympathetic denervation for resistant hypertension: a multicentre safety and proof-of-principle cohort study. Lancet, 2009; 373(9671): 1275-1281. Go to original source...
    12. Gosain P, et al. Renal sympathetic denervation for treatment of resistant hypertension: a systematic review. J Clin Hypertens (Greenwich), 2013; 15(1): 75-84. Go to original source... Go to PubMed...
    13. Persu A, et al. Blood pressure changes after renal denervation at 10 European expert centers. J Hum Hypertens, 2013 (doi: 10.1038/jhh.2013.88). Go to original source...
    14. Bhatt DL, et al. A controlled trial of renal denervation for resistant hypertension. N Engl J Med, 2014; 370(15): 1393-1401. Go to original source... Go to PubMed...
    15. Jung O, et al. Resistant hypertension? Assessment of adherence by toxicological urine analysis. J Hypertens, 2013; 31(4): 766-774. Go to original source... Go to PubMed...
    16. Rosa J, et al. A randomized comparison of renal denervation versus intensified pharmacotherapy including spironolactone in true-resistant hypertension. 6-months results from the Prague-15 study. Hypertension. 2015 Feb; 65(2): 407-413. doi: 10.1161/HYPERTENSIONAHA.114.04019. Epub 2014 Nov 24. Go to original source... Go to PubMed...
    17. Rosa J, et al. Importance of thorough investigation of resistant hypertension before renal denervation: should compliance to treatment be evaluated systematically? J Hum Hypertens. 2014 Nov;28(11):684-8. doi: 10.1038/jhh.2014.3. Epub 2014 Feb 6. Go to original source... Go to PubMed...
    18. Papademetriou V, et al. Catheter-based renal denervation for resistant hypertension: 12-month results of the EnligHTN I first-in-human study using a multielectrode ablation system. Hypertension, 2014; 64(3): 565-572. Go to original source... Go to PubMed...

    Return to the content


    Interventional Cardiology

    Madam, Sir,
    please be aware that the website on which you intend to enter, not the general public because it contains technical information about medicines, including advertisements relating to medicinal products. This information and communication professionals are solely under §2 of the Act n.40/1995 Coll. Is active persons authorized to prescribe or supply (hereinafter expert).
    Take note that if you are not an expert, you run the risk of danger to their health or the health of other persons, if you the obtained information improperly understood or interpreted, and especially advertising which may be part of this site, or whether you used it for self-diagnosis or medical treatment, whether in relation to each other in person or in relation to others.

    I declare:

    1. that I have met the above instruction
    2. I'm an expert within the meaning of the Act n.40/1995 Coll. the regulation of advertising, as amended, and I am aware of the risks that would be a person other than the expert input to these sites exhibited

    No
    Yes

    If your statement is not true, please be aware
    that brings the risk of danger to their health or the health of others.