Interv Akut Kardiol 2011; 10(5-6): 254-255
The PRODIGY study: at last we know how to treat with clopidogrel after coronary angioplasty
- 1 Kardiologické centrum Agel, Pardubice
- 2 III. interní klinika Všeobecné fakultní nemocnice 1. LF UK, Praha
The PRODIGY study is the first randomized prospective study to compare short-term (6 months) and long-term (24 months) dual antiplatelet
therapy after coronary stent implantation. Prevention of ischaemic complications in patients is comparable in both types of treatment.
Long-term dual antiplatelet therapy results in a significantly higher rate of severe bleeding complications and this risk increases with
the duration of treatment. The facts revealed are serious and should lead to modifications of the guidelines for the treatment of patients
after coronary stent implantation.
Keywords: clopidogrel, drug-eluting stents, dual antiplatelet therapy
Published: November 1, 2011 Show citation
References
- Valgimigli M. Prolonging dual antiplatelet treatment after grading stent-induced intimal hyperplasia study. ESC Congress 2011, Hot Line III, 30. 8. 2011, Paris.
- White HD. Do we need another bleeding definition? What does the Bleeding Academic Research Consortium definition have to offer? Curr Opin Cardiol 2011; 26: 275-278.
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