Interv Akut Kardiol. 2009;8(5):271-272

The PLATO study - the birth of an ideal antiplatelet therapy ?

Ivo Varvařovský
Kardio-Troll, pracoviště invazivní kardiologie, Krajská nemocnice, Pardubice

Ticagrelor, direct reversible inhibitor P2Y12 platelet receptor, significantly reduced the rate of death from vascular causes, myocardial

infarction and stroke in patients with acute coronary syndromes. First in the history of clinical trials, dual antiplatelet therapy reduced the

all-cause mortality. This treatment success was reached without an increase in the rate of overall major bleeding, but with an increase

in the rate of non-procedure-related bleeding in patients treated with ticagrelor.

Keywords: ticagrelor, clopidogrel, dual antiplatelet therapy.

Published: November 20, 2009  Show citation

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Varvařovský I. The PLATO study - the birth of an ideal antiplatelet therapy ? Interv Akut Kardiol. 2009;8(5):271-272.
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    References

    1. Wallentin L, Becker RC, Budaj A. Ticagrelor versus clopidogrel in patients with acute coronary syndromes. N Engl J Med 2009; 361: 1045-1057. Go to original source... Go to PubMed...

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