Interv Akut Kardiol. 2009;8(5):264

More or less a disease of three coronary arteries and what next ?

Petr Kala
Interní kardiologická klinika FN a LF MU v Brně

Coronary artery disease despite its modern treatmen belongs to the main causes of mortality of the czech population. The optimal treatment

strategy should be based not just on the coronary disease morphology but also and especially on its functional significance. Coronary

angiography often does not provide enough information and the investigation should be followed by the functional testing, at least

in the borderline lesions (40 – 70 %). To perform the myocardial fractional flow reserve measurement just in the cathlab is besides the

non-invasive testing a very practical tool offered to the interventional cardiologist. This principle of this method is as follows: at physiological

conditions there is no pressure difference between aorta and epicardial coronary vessels. On the opposite the coronary stenosis

leads to the distal pressure drop invasively measured (1,0 means the normal value vs. less than 0,80 or even 0,75 means the significant

stenosis causes myocardial ischemia). The measurement has to be performed during maximal myocardial hyperemia provoked pharmacologically.

At present we should describe the coronary artery disease according to its angiographical and functional significance

indicating the potential revascularisation. In the case of coronary intervention (PCI) the final treatment consists from the drug-eluting

or bare-metal stent implantation. Here described videocase should demonstrate such a complex and relatively new approach.

Keywords: coronary artery disease, coronary intervention, coronary stent, myocardial fractional flow reserve.

Published: November 20, 2009  Show citation

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Kala P. More or less a disease of three coronary arteries and what next ? Interv Akut Kardiol. 2009;8(5):264.
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