Interv Akut Kardiol. 2007;6(4):135-138
For nearly 50 years, the right ventricular apex (RVA) has been used as the elective pacing site for permanent pacing in bradyarrhythmias. Experimental and clinical studies, however, suggest that RVA pacing contributes to marked asynchrony of ventricular activation which is associated with abnormalities in regional coronary perfusion and metabolism. It might result in impairment of systolic and diastolic LV function. Long-term observational studies suggest that even structural changes may occur (remodelling). Alternative pacing sites which may reduce these adverse changes were tested in either acute or chronic studies, some of them have determined the superiority of more physiological ventricular pacing. We believe that there is a reason to change our clinical practise and not to continue in RVA pacing.
Published: October 23, 2007 Show citation