Interv Akut Kardiol. 2005;4(2):94-96

MITRAL VALVE REGURGITATION IN PATIETS WITH LOW EJECTION FRACTION

Petr Pavel1, Jan Vojáček2,3
1 Kardiochirurgická klinika 2. LF FN Motol, Praha
2 I. interní klinika Fakultní nemocnice v Hradci Králové
3 Kardiocentrum dospělých, oddělení invazivní kardiologie interní kliniky 2. LF UK a FN Motol, Praha

Syptomatic mitral valve regurgitation of both ischaemic and nonischaemic origin imparts a haemodynamic burden on the left ventricle and is a significant negative prognostic factor. Decision making whether to correct valve regurgitation or not is still under debate. Mitral valve repair may improve left ventricular function after surgery not only in patients with structural valve disease, but also in selected cases secondary to ischaemic heart disease or dilated cardiomyopathy. Correction of moderate IMR in patients submitted to CABG is therefore currently carried out, although this issue remains controversial. Mitral valve repair is superior to mitral valve replacement since it better preserves left ventricular function following surgery. Increasing age and a low ejection fraction are predictors of mortality.

Keywords: Key words: mitral regurgitation, ischemic mitral regurgitation, cardiomyopathy.

Published: January 1, 2006  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Pavel P, Vojáček J. MITRAL VALVE REGURGITATION IN PATIETS WITH LOW EJECTION FRACTION. Interv Akut Kardiol. 2005;4(2):94-96.
Download citation

References

  1. Dreyfus G, Milaiheanu S. Mitral valve repair in cardiomyopathy, J Heart Lung Transplant, 2000; 19: Suppl 73-76. Go to original source...
  2. Černý Š, Benešová M, Jehlička P, Křiváček P, Jirásek V. Ischemická mitrální regurgitace. Mýtus, nebo realita? I. sjezd České společnosti kardiovaskulární chirurgie. 11.-12. 11. 2004. In Abst. 2004: 48.
  3. Carabello BA. Is it ever too late to operate on the patient with valvular heart disease? J. Am Col. Cardiology 2004; 44: 376-83. Go to original source... Go to PubMed...
  4. Carabello BA. The pathophysiology of mitral regurgitation (review). J Heart Valve Dis 2000; 9: 600-609. Go to PubMed...
  5. Thourani VH, Weintraub WS, Guzton RA, et al. Outcomes and long-term survival for patients undergoing mitral valve repair versus replacement: effect of age and concomitant coronary artery bypass grafting. Circulation 2003; 108: 298-302. Go to original source... Go to PubMed...
  6. Bach DS, Bolling SF. Improvement followin correction of secondary mitral regurgitation in end-stage cardiomyopathy with mitral annuloplasty. Am J Cardiology 1996; 68: 966-969. Go to original source... Go to PubMed...
  7. Rozich JD, Carabello BA, Usher BW, Kratz JM, Bell AR, Zile MR. Mitral valve replacement wih and without chordal preservation in patients with chronic mitral regurgitation: mechanisms on differences on post-operative ejection performance. Circulation 1992; 86: 1718-1726. Go to original source... Go to PubMed...
  8. Sarris GE, Cahill PD, Hansen DE, Derby GC, Miller DC. Restoration of left ventriculat systolic function performance after reattachment of the mitral chordae tendinae: The importance of valvular-ventricular interaction. JThorac Cardiovasc Surg 1988; 95: 969-979. Go to original source...
  9. David TE, Uden D, Strauss HD. The importance of the mitral appartus in left ventricular function after correction of mitral regurgitation. Circulation. 1983; 68: 76-82.
  10. Cohn LH, Rizzo, RJ, Adams DH, et al. The effect of pathophysiology on the surgicel treatment of ischemic mitral regurgitation: operative and late risk of repair versus replacement.Eur J Cardio-Thor Surg 1995; 9: 568-574. Go to original source... Go to PubMed...
  11. Lamas GA, Mitchell GF, Flaker MD, et al. for Survival and Ventricular Enlargement Investigators. Clinical signifikance of mitral regurgitation after acute myocardial infarction. Circulation 197; 96: 827-833.
  12. Tcheng JE, Jackman JD, Nelson CL, et al. Outcome of patients sustaining acute ischemic mitral regurgitation during myocardial infarcion. Ann Intern Med 1992; 117: 18-24. Go to original source... Go to PubMed...
  13. Gorman RC, McCaughan JS, Ratcliffe MB, et al. A three-dimensional analysis of papillary muscle spatial relationships in acute postinfarction mitral insufficiency. Surg. Forum. 1994; 45: 330.
  14. Kaul S, Spotnitz W, Glasheen WP, et al. Mechanism of ischemic mitral regurgitation: an experimental evaluation. Circulation. 1991; 84: 2167-2180. Go to original source... Go to PubMed...
  15. Jouan J, Tapia M, Cook RC, Lansac E, Acar C. Ischemic mitral valve prolapse: mechanisms and implications for valve repair Eur. J. Cardio-Thor Surg. 2004; 26: 1112-1117. Go to original source... Go to PubMed...
  16. Rashid AM, Gillinov AM, McCarthy P, Blackstone EH, Apperson-Hansen C, Quin JX, Agler D, Shiota T, Cosgrove DM. Annular geometry and motion in Human ischemic mitral regurgitation: Novel assesment with three-dimensional echocardiography and computer reconstruction. Ann Thor Surg 2004; 78: 2063-2068. Go to original source... Go to PubMed...
  17. Kanzaki H, Bazaz R, Schwartzman D, Dohi K, Sade LE, Gorcsan J III. Mechanism for immediate reduction in mitral regurgitation after cardiac resynchronization therapy. Insights from mechanical activation strain mapping. J American Coll Cardiology 2004; 44: 619-1627. Go to original source... Go to PubMed...
  18. Trichon BH, Glower DD, Shaw LK, et al. Survival after coronary revascularization, with and without mitral valve surgery in patients with ischemic mitral regurgitation. Circulation. 2003; 108 (suppl II): 103-110. Go to original source... Go to PubMed...
  19. Hsi-Yu Yu, Mao-Yuan Su, Ta-Yu Liao, Hsu-Hsia Peng, Fang-Yue Lin, Wen-Yih Isaac Tseng. Functional mitral regurgitation in chronic ischemic coronary artery disease: Analysis of geometric alterations of mitral apparatus with magnetic resonance imaging. J Thor Cardovasc Surg 2004; 128: 543-551. Go to original source... Go to PubMed...
  20. Duran J. Osobní sdělení.
  21. Duarte IG, Shen Y, MacDonald MJ, Jones EL, Craver JM, Guyton RA. Treatment of moderate mitral regugitation and coronary disease by cortonary by-pass alone: late results. Ann Thor Surg 1999; 68 (2): 426-430. Go to original source... Go to PubMed...
  22. Siepelt RG, Schoendube FA, Vasquez-Jimenez JF, Doerge H, Voss M, Messmer BJ. Combined mitral valve and coronary artery surgery: ischemic versus non-ischemic mitral valve disease. Eur J Cardiothorac Surg 2001; 20(2): 270-275. Go to original source... Go to PubMed...
  23. Aklog L, Filsoufi F, FloresKQ, Chen RH, et al. Does Coronary artery bypass grafting alone correct moderate ischemic mitral regurgitation? Circulation 2001; 104(suppll): 68-75. Go to original source... Go to PubMed...
  24. McGee E C, Gillinov AM, Blackstone EH, Rajeswaran J, Cohen G, Najam F, Shiota T, Sabik J, Lytle BW, McCarthy PM, Cosgrove DM. Recurrent mitral regurgitation after annuloplasty for functional ischemic mitral regurgitation. J Thor Cardiovasc Surg 2004; 128: 916-924. Go to original source... Go to PubMed...
  25. Guy TS IV, Moainie SL, Gorman JH III, et al. Prevention of ischemic mitral regurgitation does not influence the outcome of remodeling after posterolateral myocardial infarction J Am Coll Cardiol 2004; 43: 377-383. Go to original source... Go to PubMed...
  26. Diodato MD, Moon MR, Pasque MK, et al. Repair of ischemic mitral regurgitation does not increase mortality or improve long-term survival in patients undergoing coronary artery revascularization: A propensity analysis. Ann Thor Surg 2004; 78: 794-799. Go to original source... Go to PubMed...




Interventional Cardiology

Madam, Sir,
please be aware that the website on which you intend to enter, not the general public because it contains technical information about medicines, including advertisements relating to medicinal products. This information and communication professionals are solely under §2 of the Act n.40/1995 Coll. Is active persons authorized to prescribe or supply (hereinafter expert).
Take note that if you are not an expert, you run the risk of danger to their health or the health of other persons, if you the obtained information improperly understood or interpreted, and especially advertising which may be part of this site, or whether you used it for self-diagnosis or medical treatment, whether in relation to each other in person or in relation to others.

I declare:

  1. that I have met the above instruction
  2. I'm an expert within the meaning of the Act n.40/1995 Coll. the regulation of advertising, as amended, and I am aware of the risks that would be a person other than the expert input to these sites exhibited


No

Yes

If your statement is not true, please be aware
that brings the risk of danger to their health or the health of others.